Organoruthenium glycomimetics as selective galectin-1 inhibitors
Hamala, Vojtěch
2023 - anglický The prepared organoruthenium glycomimetics demonstrated sin gle unit nanomolar affinity to Gal-1 and over four orders of magnitude\nhigher selectivity to Gal-1 in comparison to Gal-3. The organoruthe nium galectin inhibitors were found to be nontoxic to both cancer and\nnoncancerous cell lines. Selected complexes showed an in vitro an timigratory effect against invasive cancer cell lines MDA-MB-231 and\nSK-OV-3. Klíčová slova: galectin inhibitors; glycomimetcs; carbohydrates Plné texty jsou dostupné v digitálním repozitáři NUŠL Organoruthenium glycomimetics as selective galectin-1 inhibitors

The prepared organoruthenium glycomimetics demonstrated sin gle unit nanomolar affinity to Gal-1 and over four orders of magnitude\nhigher selectivity to Gal-1 in comparison to Gal-3. The organoruthe ...

Hamala, Vojtěch
Ústav chemických procesů, 2023

Use of photoautotrophic microorganisms in bioremediation of surface waters
Mušálková, Petra
2023 - anglický Extensive experimental work has been executed to examine suitability of the proposed approach. Throughout the experiments, phosphorus concentration in the media was measured spectrophotometrically, to confirm the amount of phosphorus uptake,\nthe intracellular phosphorus concentration was analyzed by ICP-OES spectrophotometry.\n Klíčová slova: photoautotrophic microorganisms; surface water; phosphorus; bioremediation Plné texty jsou dostupné v digitálním repozitáři NUŠL Use of photoautotrophic microorganisms in bioremediation of surface waters

Extensive experimental work has been executed to examine suitability of the proposed approach. Throughout the experiments, phosphorus concentration in the media was measured spectrophotometrically, to ...

Mušálková, Petra
Ústav chemických procesů, 2023

Investigation of recycling possibilities of discarded photovoltaic solar panels
Šperlich, Antonín
2023 - anglický This work aims to find an economically effective and industrially feasible method of how to recycle discarded photovoltaic solar panels. Performed experiments determined the exact composition of photovoltaic solar panels and the advantages and disadvantages of the treatment mentioned in the literature. Results will be used for a full-scale industrial unit design for solar photovoltaic panels recycling.\n Klíčová slova: photovoltaic solar panels; recycling; experiments Plné texty jsou dostupné v digitálním repozitáři NUŠL Investigation of recycling possibilities of discarded photovoltaic solar panels

This work aims to find an economically effective and industrially feasible method of how to recycle discarded photovoltaic solar panels. Performed experiments determined the exact composition of ...

Šperlich, Antonín
Ústav chemických procesů, 2023

The effect of meteorology and aerosol size distribution on light scattering properties at a rural background site in Central Europe
Suchánková, Lenka
2023 - anglický The aim of this study is to characterize the light scattering properties of aerosols at the rural background site National Atmospheric\nObservatory Košetice (NAOK; 49°34’20.787”N, 15°4’48.155”E) in Central Europe, namely the coefficients of total light scattering (σsp) and backscattering (σbsp), the Ångström exponent (SAE), the backscattering ratio (b), and the asymmetry factor (g), with special attention to the influence of meteorology and aerosol size distribution on these properties. We measured σ𝑠𝑝 and σ𝑏𝑠𝑝 at three wavelengths (450, 550, and 700 nm) using the Integrating Nephelometer TSI 3563 (PM10 inlet). The measurements were performed from August 16, 2012 to December 31, 2019. Klíčová slova: properties aerosols; backscattering; measurements Plné texty jsou dostupné v digitálním repozitáři NUŠL The effect of meteorology and aerosol size distribution on light scattering properties at a rural background site in Central Europe

The aim of this study is to characterize the light scattering properties of aerosols at the rural background site National Atmospheric\nObservatory Košetice (NAOK; 49°34’20.787”N, 15°4’48.155”E) in ...

Suchánková, Lenka
Ústav chemických procesů, 2023

N-alkylation of a lysergic acid derivative under PTC conditions in a continuous arrangement using sonication
Jaklová, Natalie
2023 - anglický This contribution focuses on the application of sonication to the synthesis of a methyl ester of the 1-methyl-10α-methoxydihydrolysergic acid (MeLUME). Klíčová slova: sonication; synthesis; methyl ester Plné texty jsou dostupné v digitálním repozitáři NUŠL N-alkylation of a lysergic acid derivative under PTC conditions in a continuous arrangement using sonication

This contribution focuses on the application of sonication to the synthesis of a methyl ester of the 1-methyl-10α-methoxydihydrolysergic acid (MeLUME).

Jaklová, Natalie
Ústav chemických procesů, 2023

PROCESSING OF THE DATA MEASURED WITH CLOUD CONDENSATION NUCLEI COUNTER IN YEAR 2020 FOR SUBMISSION TO EBAS DATABASE
Moravec, Pavel; Jindra, Tomáš; Wagner, Zdeněk; Ždímal, Vladimír
2023 - anglický Aerosol particles in the atmosphere that allow water vapor to condense and form cloud droplets are called Cloud Condensation Nuclei (CCN). Elevated concentrations of CCN tend to increase the concentration and decrease the size of cloud droplets. This can lead to suppression of precipitation in shallow and short-lived clouds and to greater convective overturning and more precipitation in deep convective clouds, Rose et al.(2010). The response of cloud properties and precipitation processes to increasing anthropogenic aerosol concentrations represents one of the largest uncertainties in the current understanding of climate change. One of the fundamental challenges is to determine the ability of aerosol particles to act as CCN under relevant atmospheric conditions. Knowledge of the spatial and temporal distribution in the atmosphere is essential to incorporate the effects of CCN into meteorological models of all scales, Huang et al. (2007). Long-term CCN measurements are performed at aerosol monitoring sites such as those forming ACTRIS (Aerosols, Clouds, and Trace Gases Research Infrastructure) network. Measured data are then submitted to the EBAS database, where they are available for the other ACTRIS researchers. In this paper, we present our experience with the processing of the data measured with CCNC for submission to the EBAS database. The data prepared for submission to EBAS from year 2020 are also presented. Klíčová slova: atmospheric aerosols; CCNC; cloud condensation nuclei concentrations Plné texty jsou dostupné v digitálním repozitáři NUŠL PROCESSING OF THE DATA MEASURED WITH CLOUD CONDENSATION NUCLEI COUNTER IN YEAR 2020 FOR SUBMISSION TO EBAS DATABASE

Aerosol particles in the atmosphere that allow water vapor to condense and form cloud droplets are called Cloud Condensation Nuclei (CCN). Elevated concentrations of CCN tend to increase the ...

Moravec, Pavel; Jindra, Tomáš; Wagner, Zdeněk; Ždímal, Vladimír
Ústav chemických procesů, 2023

DRONE-BASED VERTICAL MEASUREMENTS OF BLACK CARBON AEROSOLS AT A RURAL BACKGROUND AND AN URBAN SITE
Julaha, Kajal; Zíková, Naděžda; Ždímal, Vladimír
2023 - anglický Black Carbon (BC) aerosols are primary particles emitted into the atmosphere as a by-product of incomplete combustion processes. BC absorbs solar radiation and altersthe radiation budget of the Earth(Bond et al., 2013). The radiative properties of BC heavily depend on its vertical profiles(Haywood and Ramaswamy, 1998). For example, BC in the free troposphere can enhance its radiative forcing by trapping energy emitted from lower cloud layers. \nThe modeling-based studies on BC vertical distribution are particularly poor (Chen et al., 2022), creating a need to measure the vertical distribution of BC on a regional scale,from areas characterized by anthropogenic emissions from the ground to those characterized by long-range transport(Ramana et al., 2010). Among all the other methods, drones have recently gained popularity because of their high-cost efficiency, flexibility, and mobility. Besides comparing BC aerosol vertical distribution at an urban and a regional background site, this study also calibrates drone measurements using a 230-meter tower. Klíčová slova: vertical profile; drone; rural background Plné texty jsou dostupné v digitálním repozitáři NUŠL DRONE-BASED VERTICAL MEASUREMENTS OF BLACK CARBON AEROSOLS AT A RURAL BACKGROUND AND AN URBAN SITE

Black Carbon (BC) aerosols are primary particles emitted into the atmosphere as a by-product of incomplete combustion processes. BC absorbs solar radiation and altersthe radiation budget of the ...

Julaha, Kajal; Zíková, Naděžda; Ždímal, Vladimír
Ústav chemických procesů, 2023

An Enzymatic Biosensor with Amperometric Detection in a Flow Injection Analysis for the Determination of L-lactic Acid: Development and Application
Tvorynska, Sofiia; Barek, J.; Josypčuk, Bohdan
2023 - anglický An amperometric biosensor consisting of an enzymatic mini-reactor (lactate oxidase covalently\nattached to −NH2 functionalized mesoporous silica powder SBA−15 using glutaraldehyde) and\na silver amalgam-based screen-printed electrode acting as a transducer was developed for the\ndetermination of L-lactic acid (LA) in FIA. The detection potential of −0.9 V vs. Ag pseudoreference\nelectrode was applied for cathodic detection of enzymatically consumed oxygen.\nUnder the optimized conditions, the constructed biosensor enabled selective determination of\nLA with a micromolar limit of detection. Importantly, the proposed biosensor represented\nexcellent operational stability after ≥350 measurements. Finally, it was successfully applied to\nreal sample analysis. Klíčová slova: L-lactic acid; Lactate oxidase; Amperometric biosensor; silver amalgam Plné texty jsou dostupné na vyžádání prostřednictvím repozitáře Akademie věd. An Enzymatic Biosensor with Amperometric Detection in a Flow Injection Analysis for the Determination of L-lactic Acid: Development and Application

An amperometric biosensor consisting of an enzymatic mini-reactor (lactate oxidase covalently\nattached to −NH2 functionalized mesoporous silica powder SBA−15 using glutaraldehyde) and\na silver ...

Tvorynska, Sofiia; Barek, J.; Josypčuk, Bohdan
Ústav fyzikální chemie J. Heyrovského, 2023

24. ročník Školy hmotnostní spektrometrie. KURZ B - Základy ICP-MS
Cvačka, Josef; Vlk, Mikuláš; Vrkoslav, Vladimír; Hubálek, Martin
2023 - český Klíčová slova: mass spectrometry; ICP-MS; speciation analysis Plné texty jsou dostupné na vyžádání prostřednictvím repozitáře Akademie věd. 24. ročník Školy hmotnostní spektrometrie. KURZ B - Základy ICP-MS

Cvačka, Josef; Vlk, Mikuláš; Vrkoslav, Vladimír; Hubálek, Martin
Ústav organické chemie a biochemie, 2023

24. ročník Školy hmotnostní spektrometrie. KURZ A - Interpretace spekter EI
Cvačka, Josef; Vlk, Mikuláš; Vrkoslav, Vladimír; Hubálek, Martin
2023 - český Klíčová slova: mass spectrometry; EI; data analysis Plné texty jsou dostupné na vyžádání prostřednictvím repozitáře Akademie věd. 24. ročník Školy hmotnostní spektrometrie. KURZ A - Interpretace spekter EI

Cvačka, Josef; Vlk, Mikuláš; Vrkoslav, Vladimír; Hubálek, Martin
Ústav organické chemie a biochemie, 2023