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4th CCP Phenogenomics Conference abstract book
Sedláček, Radislav
2022 - anglický
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic focus of the 2022 Conference. The Conference provided again an excellent opportunity to support networking and interactions among the researchers, CCP staff, users and experts from the commercial sector.
Klíčová slova:
phenogenomics; rare diseases; gene therapy; experimental models; delivery of therapies
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
4th CCP Phenogenomics Conference abstract book
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic ...
4th CCP Phenogenomics Conference abstract book
Sedláček, Radislav
2022 - anglický
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic focus of the 2022 Conference. The Conference provided again an excellent opportunity to support networking and interactions among the researchers, CCP staff, users and experts from the commercial sector.
Klíčová slova:
phenogenomics; rare diseases; gene therapy; experimental models; delivery of therapies
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
4th CCP Phenogenomics Conference abstract book
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic ...
3rd CCP Phenogenomics Conference 2021: Abstract Book
Sedláček, Radislav
2021 - anglický
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including covid-19, which focused on translation of the basic research into the application. The Conference provided an excellent opportunity to support networking and interactions among the CCP users and experts.
Klíčová slova:
phenogenomics; human diseases; mouse models; preclinical development; covid-19
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
3rd CCP Phenogenomics Conference 2021: Abstract Book
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including ...
2nd CCP Phenogenomics Conference 2020: Abstract Book
Sedláček, Radislav
2020 - anglický
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including covid-19, which focused on translation of the basic research into the application. The Conference provided an excellent opportunity to support networking and interactions among the CCP users and experts.
Klíčová slova:
phenogenomics,; human diseases; mouse models; preclinical development
Plné texty jsou dostupné v digitálním repozitáři NUŠL
2nd CCP Phenogenomics Conference 2020: Abstract Book
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including ...
2nd CCP Phenogenomics Conference 2020
Sedláček, Radislav
2020 - anglický
The conference was divided into two blocks. The block focused on the theme “From chemistry via preclinical pipeline to therapeutics“, which emphasized the translation of the basic research into the application. The second block was specifically devoted to presentation of CCP users and cooperation partners projects working in the field of immunology, hematology, genetic base of diseases, and neurobiology.
Klíčová slova:
Phenogenomics; therapeutics; immunity; genetic base of diseases
Plné texty jsou dostupné v digitálním repozitáři Akademie Věd.
2nd CCP Phenogenomics Conference 2020
The conference was divided into two blocks. The block focused on the theme “From chemistry via preclinical pipeline to therapeutics“, which emphasized the translation of the basic research into the ...
Characterization of peptide proteinase inhibitors isolated from boar seminal plasma
Jelínková, Petra; Tichá, M.; Jonáková, Věra
2003 - anglický
Most of proteins of boar seminal plasma are present in this medium under physiological conditions in the form of aggregates and not of monomers. In the present communication we have shown that not only spermadhesins, but also proteinase inhibitors participate in the formation of associated complexes. Proteinase inhibitors were found after gel chromatographic separation mainly in the fraction with the lowest relative molecular mass. Two different types of serine proteinase inhibitors were isolated from boar seminal plasma ů (i) glycosylated inhibitor with Mr 12 kDa, (ii) non-glycosylated sperm-associated acrosin inhibitor with Mr 8 kDa, and a new type of low molecular weight protein that is probably composed of two subunits coupled by the -S-S- bridge. The proteinase inhibitor with Mr 8 kDa was proved to form a heterodimer with AQN 1 spermadhesin under physiological conditions, whereas inhibitor with Mr 12 kDa forms homodimers.
Klíčová slova:
proteinase inhibitors, aggregated forms, boar seminal plasma
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Characterization of peptide proteinase inhibitors isolated from boar seminal plasma
Most of proteins of boar seminal plasma are present in this medium under physiological conditions in the form of aggregates and not of monomers. In the present communication we have shown that not ...
Properties of serine proteinase inhibitors from boar seminal plasma
Jelínková, Petra; Maňásková, Pavla; Tichá, M.; Jonáková, Věra
2002 - anglický
Inhibitors of proteinases are important components of seminal plasma. Their biological function in seminal plasma is to protect protein components of seminal plasma and male and female reproductive tracts against proteolytic degradation. My work is concentrated on characterization of inihibitors found in seminal plasma.
Klíčová slova:
inhibitors; seminal plasma; boar serine proteinase inhibitors; inhibitory
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Properties of serine proteinase inhibitors from boar seminal plasma
Inhibitors of proteinases are important components of seminal plasma. Their biological function in seminal plasma is to protect protein components of seminal plasma and male and female reproductive ...
Study of aggregated forms of proteinase inhibitors from boar seminl plasma by gel chromatography
Jelínková, Petra; Maňásková, Pavla; Tichá, M.; Jonáková, Věra
2002 - anglický
Most of proteins in seminal plasma exist under physiological conditions in the form of aggregates. The study of the presence of proteinase inhibitosr in different associated forms of boar seminal plasma proteins is the subject of our present communication.
Klíčová slova:
Gel chromatography; proteinase inhibitors; seminal plasma
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Study of aggregated forms of proteinase inhibitors from boar seminl plasma by gel chromatography
Most of proteins in seminal plasma exist under physiological conditions in the form of aggregates. The study of the presence of proteinase inhibitosr in different associated forms of boar seminal ...
Protein interactions involved in the formation of aggregated forms of boar seminal plasma proteins
Maňásková, Pavla; Balínová, P.; Tichá, M.; Jonáková, Věra
2002 - anglický
Mutual interactions of isolated proteins were tested by means of gel chromatography. The results obtained confirmed an existence of interactions between spermadhesins of the AQN and AWN families as well as between proteins involved in the formation of heterodimer PSPI/PSPII.
Klíčová slova:
spermadhesins; aggregates; aggregated forms
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Protein interactions involved in the formation of aggregated forms of boar seminal plasma proteins
Mutual interactions of isolated proteins were tested by means of gel chromatography. The results obtained confirmed an existence of interactions between spermadhesins of the AQN and AWN families as ...
Effect of endocrine disruptors on the microtubules of MCF-7 cells
Pěknicová, Jana; Kubátová, Alena; Kyselová, Vendula; Buckiová, Daniela; Paleček, J.; Dráber, Pavel
2002 - anglický
Klíčová slova:
microtubules; endocrine disruptor; MCF-7 cell
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Effect of endocrine disruptors on the microtubules of MCF-7 cells
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