Number of found documents: 259
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Book of Abstracts and Programme
Beneš, Hynek; Starý, Zdeněk
2024 - English
The Book of Abstracts and Programme contains time order and the summaries of all the contributions to the international conference “Polymers for Sustainable Future 2024” was organized simultaneously as the 85th Prague Meeting on Macromolecules (PMM) and 11th Conference on Green Chemistry and Nanotechnologies in Polymeric Materials. The participants presented 84 lectures and 91 posters. Keywords: polymers; sustainable; green chemistry Available at various institutes of the ASCR
Book of Abstracts and Programme

The Book of Abstracts and Programme contains time order and the summaries of all the contributions to the international conference “Polymers for Sustainable Future 2024” was organized simultaneously ...

Beneš, Hynek; Starý, Zdeněk
Ústav makromolekulární chemie, 2024

Surfactant-free silver nanofluids as liquid systems with neuromorphic potential
Nikitin, D.; Biliak, K.; Lemke, J.; Protsak, M.; Pleskunov, P.; Tosca, M.; Ali-Ogly, S.; Červenková, V.; Adejube, B.; Bajtošová, L.; Černochová, Zulfiya; Prokeš, J.; Křivka, I.; Biederman, H.; Faupel, F.; Vahl, A.; Choukourov, A.
2024 - English
Neuromorphic engineering is a rapidly developing branch of science that aims to implement the unique attributes of biological neural networks in artificial devices. Most neuromorphic devices are based on the resistive switching effect, which involves changing the device’s conductivity in response to an external electric field. For instance, percolating nanoparticle (NP) networks produced by gas aggregation cluster sources (GAS) show collective spiking behavior in conductivity reminiscent of brain-like dynamics. Nevertheless, the problem of dynamic spatial reconfiguration in solid-state neuromorphic systems remains unsolved. Herein, novel nanofluids with resistive switching properties are proposed as neuromorphic media. They are produced by depositing silver NPs from GAS into vacuum-compatible liquids (paraffin, silicon oil, and PEG) without the use of surfactants or other chemicals. When the electric field is applied between two electrodes, the migration of NPs toward biased electrode is detected in all liquids. The electrophoretic nature of the NP movement was proved by means of ζ-potential measurements. Such movement led to the self-assembly of NPs in conductive paths connecting the electrodes and, as a result, to resistive switching. The electrical response was strongly dependent on the dielectric constant of the base liquid. The Ag-PEG nanofluid demonstrated the best switching performance reproducible during several tens of current-voltage cycles. The growth of flexible and reconfigurable conductive filaments in nanofluids makes them suitable media for potential realization of 3D neural networks. Keywords: nanofluid; gas aggregation cluster source; ζ-potential, electrophoresis Available at various institutes of the ASCR
Surfactant-free silver nanofluids as liquid systems with neuromorphic potential

Neuromorphic engineering is a rapidly developing branch of science that aims to implement the unique attributes of biological neural networks in artificial devices. Most neuromorphic devices are based ...

Nikitin, D.; Biliak, K.; Lemke, J.; Protsak, M.; Pleskunov, P.; Tosca, M.; Ali-Ogly, S.; Červenková, V.; Adejube, B.; Bajtošová, L.; Černochová, Zulfiya; Prokeš, J.; Křivka, I.; Biederman, H.; Faupel, F.; Vahl, A.; Choukourov, A.
Ústav makromolekulární chemie, 2024

Temoporfin-conjugated upconversion nanoparticles for NIR-induced photodynamic therapy of pancreatic cancer
Shapoval, Oleksandr; Větvička, D.; Kabešová, M.; Engstová, Hana; Horák, Daniel
2024 - English
Photodynamic therapy (PDT), a clinically approved cancer treatment strategy, has the potential to cure pancreatic cancer with minimal side effects. PDT primarily uses visible wavelengths to directly activate hydrophobic photosensitizers, which may be insufficient for deep-seated cancer cells in clinical practice due to poor penetration. Upconversion nanoparticles (UCNPs) serve as an indirect excitation source to activate photosensitizers (PSs) in the NIR region, overcoming the limitations of molecular PSs such as hydrophobicity, non-specificity, and excitation in the UV/Vis region. Here, monodisperse upconversion NaYF4:Yb3+, Er3+, Fe2+ nanoparticles (UCNPs) have been surface-engineered with poly(methyl vinyl ether-alt-maleic acid) (PMVEMA) and temoporfin (mTHPC), a clinically used PDT prodrug, for near-infrared (NIR) light-triggered PDT of pancreatic cancer. The incorporation of Fe2+ ions into the particles increased the fluorescence intensity in the red region matching the activation wavelength of mTHPC. Covalent binding of mTHPC to the surface of UCNP@PMVEMA particles provided colloidally stable conjugates enabling generation of singlet oxygen. In vitro cytotoxicity and photodynamic activity of the particles were evaluated using INS-1E rat insulinoma and Capan-2 and PANC-01 human pancreatic adenocarcinoma cell lines. The PDT efficacy of UCNP@PMVEMA-mTHPC conjugates after irradiation with 980 nm NIR light was tested in vivo in a pilot study on Capan-2 human pancreatic adenocarcinoma growing subcutaneously in athymic nude mice. The intratumoral administration of the nanoconjugates significantly hindered tumor growth and demonstrated promising PDT efficacy against human pancreatic cancer. Keywords: photodynamic therapy; temoporfin; upconversion nanoparticles Available in digital repository of the ASCR
Temoporfin-conjugated upconversion nanoparticles for NIR-induced photodynamic therapy of pancreatic cancer

Photodynamic therapy (PDT), a clinically approved cancer treatment strategy, has the potential to cure pancreatic cancer with minimal side effects. PDT primarily uses visible wavelengths to directly ...

Shapoval, Oleksandr; Větvička, D.; Kabešová, M.; Engstová, Hana; Horák, Daniel
Ústav makromolekulární chemie, 2024

Novel embedding resins for 3D-SEM II
Šlouf, Miroslav; Pavlova, Ewa; Strachota, Beata; Strachota, Adam; Nebesářová, Jana; Týč, Jiří; Krzyžánek, Vladislav; Skoupý, Radim
2023 - English
Research report for Thermo Fisher Scientific s. r. o., based on common project awarded by TA CR (program: National center of competence, TN01000008). Keywords: novel embedding resins; 3D-SEM microscopy; higher e-beam resistance Available at various institutes of the ASCR
Novel embedding resins for 3D-SEM II

Research report for Thermo Fisher Scientific s. r. o., based on common project awarded by TA CR (program: National center of competence, TN01000008).

Šlouf, Miroslav; Pavlova, Ewa; Strachota, Beata; Strachota, Adam; Nebesářová, Jana; Týč, Jiří; Krzyžánek, Vladislav; Skoupý, Radim
Ústav makromolekulární chemie, 2023

Novel embedding resins for 3D-SEM
Šlouf, Miroslav; Pavlova, Ewa; Strachota, Beata; Strachota, Adam; Nebesářová, Jana; Týč, Jiří; Krzyžánek, Vladislav; Skoupý, Radim
2022 - English
The report contains the detailed analysis of novel embedding resins for 3D-SEM. Keywords: novel embedding resins; 3D-SEM microscopy; higher e-beam resistance Available at various institutes of the ASCR
Novel embedding resins for 3D-SEM

The report contains the detailed analysis of novel embedding resins for 3D-SEM.

Šlouf, Miroslav; Pavlova, Ewa; Strachota, Beata; Strachota, Adam; Nebesářová, Jana; Týč, Jiří; Krzyžánek, Vladislav; Skoupý, Radim
Ústav makromolekulární chemie, 2022

XII. Czech - Slovak Conference Polymers 2022. Book of Abstracts
Chytil, Petr
2022 - English
The book of abstracts contains summaries of all contributions to the 12th Czech-Slovak Conference POLYMERS 2022, organized by the Institute of Macromolecular Chemistry of the CAS in Třešť, October 3-6, 2022. There were 33 lectures and 14 posters presented at the conference. Keywords: macromolecular chemistry; polymer materials; polymer characterization Available at various institutes of the ASCR
XII. Czech - Slovak Conference Polymers 2022. Book of Abstracts

The book of abstracts contains summaries of all contributions to the 12th Czech-Slovak Conference POLYMERS 2022, organized by the Institute of Macromolecular Chemistry of the CAS in Třešť, October ...

Chytil, Petr
Ústav makromolekulární chemie, 2022

Frontiers of Polymer Colloids: From Synthesis to Macro-Scale and Nano-Scale Applications. 84th Prague Meeting on Macromolecules. Book of Abstracts
Horák, Daniel
2022 - English
The Book of Abstracts contains the summaries of all the contributions to the international conference “Frontiers of Polymer Colloids: From Synthesis to Macro-Scale and Nano-Scale Applications” was organized simultaneously as the 84th Prague Meeting on Macromolecules (PMM). The participants presented 59 lectures and 38 posters. Keywords: macromolecular chemistry; polymer; colloids Available at various institutes of the ASCR
Frontiers of Polymer Colloids: From Synthesis to Macro-Scale and Nano-Scale Applications. 84th Prague Meeting on Macromolecules. Book of Abstracts

The Book of Abstracts contains the summaries of all the contributions to the international conference “Frontiers of Polymer Colloids: From Synthesis to Macro-Scale and Nano-Scale Applications” was ...

Horák, Daniel
Ústav makromolekulární chemie, 2022

Degradation of polycaprolactone electrospun materials - methods of analysis
Havlíčková, K.; Řezanka, M.; Kobera, Libor; Kuželová Košťáková, E.; Lukáš, D.; Jenčová, V.
2021 - English
Biodegradable electrospun materials are widely used for medical application. Polycaprolatone is polymer suitable for electrospinning technology and is very often used to create nanofibrous scaffolds for tissue engineering. The time to disintegration or biodegradation of such materials is very important here. However, testing is not entirely easy. It is not possible to create exactly body-like conditions in vitro. Moreover, it is not easy to find suitable analytical methods that would show exactly what happens in the nanofibrous polycaprolactone electrospun samples at certain stages of degradation, ie how the internal structure of decaying nanofibers changes. This paper describes the traditional use of methods for testing polycaprolatone nanofibers by enzymatically catalysed degradation. Morphological changes are studied using scanning electron microscope images. However, it also offers a non-traditional analysis of polycaprolactone electrospun materials using the ssNMR method. Keywords: electrospinning; nanofibers; enzymatic degradation Available at various institutes of the ASCR
Degradation of polycaprolactone electrospun materials - methods of analysis

Biodegradable electrospun materials are widely used for medical application. Polycaprolatone is polymer suitable for electrospinning technology and is very often used to create nanofibrous scaffolds ...

Havlíčková, K.; Řezanka, M.; Kobera, Libor; Kuželová Košťáková, E.; Lukáš, D.; Jenčová, V.
Ústav makromolekulární chemie, 2021

Career in Polymers XI, Book of Abstracts
Kobera, Libor
2019 - English
The book of abstracts contains the summaries of all the contributions to the Career in Polymers XI., workshop organized by the Institute of Macromolecular Chemistry AS CR, in Prague, 28-29 June, 2019. This meeting was organized under the auspices of UNESCO/IUPAC course in Polymer Science, and supported by Strategy AV21. Keywords: polymer science; career in polymers; UNESCO course in Polymer Science Available at various institutes of the ASCR
Career in Polymers XI, Book of Abstracts

The book of abstracts contains the summaries of all the contributions to the Career in Polymers XI., workshop organized by the Institute of Macromolecular Chemistry AS CR, in Prague, 28-29 June, 2019. ...

Kobera, Libor
Ústav makromolekulární chemie, 2019

Book of Abstracts and Programme. Polymers in Medicine 2019 - Prague Meeting on Macromolecules /83.
Etrych, Tomáš; Chytil, Petr
2019 - English
The Book of abstracts and programme contains the summaries of all the contributions to the international conference “Polymers in Medicine 2019”. The participants presented 43 lectures and 35 posters. Main conference topics were: Polymers for nanomedicine, Stimuliresponsive polymers, Polymers for advanced drug delivery, Polymers for biomedical applications, Biomaterials for tissue engineering. Keywords: polymers; drug delivery; controlled release Available at various institutes of the ASCR
Book of Abstracts and Programme. Polymers in Medicine 2019 - Prague Meeting on Macromolecules /83.

The Book of abstracts and programme contains the summaries of all the contributions to the international conference “Polymers in Medicine 2019”. The participants presented 43 lectures and 35 posters. ...

Etrych, Tomáš; Chytil, Petr
Ústav makromolekulární chemie, 2019

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