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Consistency of mathematical and experimental model of the autoparametric system
Fischer, Cyril; Náprstek, Jiří
2023 - English
This paper presents a long-overdue comparison of data obtained from experimental investigation of a spherical vibration absorber with the results of two mathematical models of the motion of a heavy sphere in a spherical surface. It shows that the danger posed by the potentially unstable self-parametric nature of the mathematical system is not too great in the case of realistic configurations, and that the values of the parameters describing the realistic structures remain within intervals corresponding to the stable behaviour of the absorber.
Keywords:
vibration absorber; rolling sphere; spherical surface; autoparametric system; structural health monitoring
Available at various institutes of the ASCR
Consistency of mathematical and experimental model of the autoparametric system
This paper presents a long-overdue comparison of data obtained from experimental investigation of a spherical vibration absorber with the results of two mathematical models of the motion of a heavy ...
Bioléčiva pohledem hmotníkáře
Hubálek, Martin; Lenčo, J.
2023 - Czech
Kurz má za cíl představit bioléčiva, která se stávají stále významnější součástí farmakoterapie závažných onemocnění. Pro kontrolu jejich kvality ve farmaceutickém průmyslu hraje důležitou roli hmotnostní spektrometrie. Uvedeme posluchače do problematiky bioléčiv, kterými jsou v tomto pohledu peptidy, proteiny, monoklonální protilátky nebo oligonukleotidy. Z pohledu analytika se zaměříme především na protilátková léčiva, podíváme se na možnosti jejich separace a analýzy pomocí hmotnostní spektrometrie, a to na úrovni intaktních proteinových molekul, protilátkových podjednotek nebo peptidů. The course aims to introduce biotherapeutics, which are becoming an increasingly important part of the pharmacotherapy of serious diseases. Mass spectrometry plays an important role for their quality control in the pharmaceutical industry. We will introduce the audience to biopharmaceuticals, which in this context are peptides, proteins, monoclonal antibodies or oligonucleotides. From the analyst's point of view, we will focus mainly on antibody drugs, looking at the possibilities of their separation and analysis by mass spectrometry, at the level of intact protein molecules, antibody subunits or peptides.
Keywords:
mass spectrometry; biopharmaceuticals; LC-MS
Available on request at various institutes of the ASCR
Bioléčiva pohledem hmotníkáře
Kurz má za cíl představit bioléčiva, která se stávají stále významnější součástí farmakoterapie závažných onemocnění. Pro kontrolu jejich kvality ve farmaceutickém průmyslu hraje důležitou roli ...
Výtečník. K významové proměně jednoho pojmu
Velek, Luboš
2023 - Czech
Studie analyzuje vznik termínu „výtečník“ a jeho významové proměny v české politice a kultuře 19. a 20. století. The study analyses the emergence of the term “výtečník” and its transformations in Czech politics and culture in the 19th and 20th centuries.
Keywords:
political culture; Bohemia, patriotic society; Habsburg monarchy
Available at various institutes of the ASCR
Výtečník. K významové proměně jednoho pojmu
Studie analyzuje vznik termínu „výtečník“ a jeho významové proměny v české politice a kultuře 19. a 20. století....
Badatelské „přelety“ mezi Čechami a Moravou. Příspěvek ke vzájemné spolupráci Innocence Ladislava Červinky a Klimenta Čermáka
Velímský, Filip
2023 - Czech
Čáslavský archeolog a muzejník Kliment Čermák navázal a po dobu svého života pak i udržoval poměrně hojné styky s řadou osobností z moravské archeologické obce. Příspěvek přináší dílčí přehled těchto kontaktů s jednotlivými badateli, zejména pak Innocencem Ladislavem Červinkou, přičemž primárně vychází z dochované korespondence a rukopisů uložených v rámci Čermákovy pozůstalosti v Literárním archivu Památníku národního písemnictví v Praze, Archivu Městského muzea a knihovny v Čáslavi a Státního okresního archivu v Kutné Hoře. Do příspěvku jsou zahrnuty i zjištěné informace o vzájemném publikování textů na stránkách spolkových periodik Muzejního a vlastivědného spolku „Včela Čáslavská“, Vlasteneckého spolku muzejního v Olomouci a Moravského archeologického klubu. Kliment Čermák, the archaeologist and museum curator in Čáslav, established and during his lifetime maintained relatively abundant contacts with a number of personalities from the Moravian archaeological community. The contribution provides a partial overview of these contacts with individual researchers, especially with Innocenc Ladislav Červinka, while is primarily based on the preserved correspondence and manuscripts stored as part of Čermák's estate in the Literary Archive of the Museum of Czech Literature in Prague, the Archive of the Municipal Museum and Library in Čáslav and the State District Archive in Kutná Hora. The contribution also includes the information about the mutual publication of texts on the pages of the periodicals of the Museum and Patriotic Society „Včela Čáslavská“, the Patriotic Museum Society in Olomouc and the Moravian Archaeological Club.
Keywords:
Kliment Čermák; Innocenc Ladislav Červinka; archaeology; collaboration between researchers; correspondence
Available at various institutes of the ASCR
Badatelské „přelety“ mezi Čechami a Moravou. Příspěvek ke vzájemné spolupráci Innocence Ladislava Červinky a Klimenta Čermáka
Čáslavský archeolog a muzejník Kliment Čermák navázal a po dobu svého života pak i udržoval poměrně hojné styky s řadou osobností z moravské archeologické obce. Příspěvek přináší dílčí přehled těchto ...
Jak se kde v Česku mluví aneb Co víme o dialektech češtiny
Ireinová, Martina; Konečná, Hana
2023 - Czech
Přednáška se zabývá rozdílnými dialekty různé mluvy na Moravě a ve Slezsku. The lecture deals with different dialects of different speeches in Moravia and Silesia.
Keywords:
Czech language; dilects; Moravia; Silesia; Czech Linguistic Atlas
Available at various institutes of the ASCR
Jak se kde v Česku mluví aneb Co víme o dialektech češtiny
Přednáška se zabývá rozdílnými dialekty různé mluvy na Moravě a ve Slezsku.
The lecture deals with different dialects of different speeches in Moravia and Silesia.
Ceramic protection of anti-corrosion layers of 3-glycidyloxypropyl-triethoxysilane on steel
Pokorný, P.; Prodanović, N.; Janata, Marek; Brožek, Vlastimil
2023 - English
There are various variations on the problem of steel reinforcement bond strength in concrete. Along with geometrical considerations, corrosion performance of steels with varying chemical compositions in interaction with variable chemical compositions of concrete are crucial. One approach is to cover steel surfaces with organosilane compounds, which increases the reinforcement resistance to corrosion in both acidic and alkaline conditions but, on the other hand, may weaken the reinforcement bond strength on concrete. The issue is resolved by intentionally forming a thin-walled, highly adhering corundum layer that is highly porous and impregnated with 3-glycidyloxypropyltriethoxysilane. This procedure also includes testing the adhesion properties between the ceramic and the metal and the cement prior to conducting a corrosion test in a chloride environment.
Keywords:
steel; concrete; ceramics
Available at various institutes of the ASCR
Ceramic protection of anti-corrosion layers of 3-glycidyloxypropyl-triethoxysilane on steel
There are various variations on the problem of steel reinforcement bond strength in concrete. Along with geometrical considerations, corrosion performance of steels with varying chemical compositions ...
On the development of a numerical model for the simulation of air flow in the human airways
Lancmanová, Anna; Bodnár, Tomáš; Sequeira, A.
2023 - English
This contribution reports on an ongoing study focusing on reduced order models for incompressible viscous fluid flow in two dimensional channels. A finite difference solver was developed using a simple implementation of the immersed boundary method to represent the channel geometry. The solver was validated for unsteady flow by comparing the obtained two-dimensional numerical solutions with analytical profiles computed from the Womersley solution. Finally the 2D model was coupled to a simple 1D extension simulating the flow in axisymmetric elastic vessel (tube). Some of the coupling principles and implementation issues are discussed in detail.
Keywords:
reduced order model; incompressible Navier-Stokes equations; finite difference approximation; coupling method
Available in digital repository of the ASCR
On the development of a numerical model for the simulation of air flow in the human airways
This contribution reports on an ongoing study focusing on reduced order models for incompressible viscous fluid flow in two dimensional channels. A finite difference solver was developed using a ...
Simulating particle-laden flows: from immersed boundaries towards model order reduction
Isoz, Martin; Kubíčková, Lucie; Kotouč Šourek, M.; Studeník, Ondřej; Kovárnová, A.
2023 - English
Particle-laden flow is prevalent both in nature and in industry. Its appearance ranges from the trans-port of riverbed sediments towards the magma flow, from the deposition of catalytic material inside particulate matter filters in automotive exhaust gas aftertreatment towards the slurry transport in dredging operations. In this contribution, we focus on the particle-resolved direct numerical simulation (PR-DNS) of the particle-laden flow. Such a simulation combines the standard Eulerian approach to computational fluid dynamics (CFD) with inclusion of particles via a variant of the immersed boundary method (IBM) and tracking of the particles movement using a discrete element method (DEM). Provided the used DEM allows for collisions of arbitrarily shaped particles, PR-DNS is based (almost) entirely on first principles, and as such it is a truly high-fidelity model. The downside of PR-DNS is its immense computational cost. In this work, we focus on three possibilities of alleviating the computational cost of PR-DNS: (i) replacing PR-DNS by PR-LES or PR-RANS, while the latter requires combining IBM with wall functions, (ii) improving efficiency of DEM contact solution via adaptively refined virtual mesh, and (iii) developing a method of model order reduction specifically tailored to PR-DNS of particle-laden flows.
Keywords:
particle-laden flow; CFD-DEM; arbitrarily-shaped particles; finite volume method
Fulltext is available at external website.
Simulating particle-laden flows: from immersed boundaries towards model order reduction
Particle-laden flow is prevalent both in nature and in industry. Its appearance ranges from the trans-port of riverbed sediments towards the magma flow, from the deposition of catalytic material ...
On Reynolds-averaged turbulence modeling with immersed boundary method
Kubíčková, Lucie; Isoz, Martin
2023 - English
The immersed boundary (IB) method is an approach in the computational fluid dynamics in which complex geometry conforming meshes are replaced by simple ones and the true simulated geometry is projected onto the simple mesh by a scalar field and adjustment of governing equations. Such an approach is particularly advantageous in topology optimizations (TO) where it allows for substantial speed-up since a single mesh can be used for all the tested topologies. In our previous work, we linked our custom IB variant, the hybrid fictitious domain-immersed boundary method (HFDIB), with a TO framework and successfully carried out an optimization under laminar flow conditions. However, to allow for optimizations of reallife components, the IB approach needs to be coupled with an affordable turbulence modeling. In this contribution, we focus on extending the HFDIB approach by the possibility to perform Reynolds-averaged simulations (RAS). In particular, we implemented the k − ω turbulence model and wall functions for closure variables and velocity.
Keywords:
immersed boundary; RAS; wall functions; CFD; OpenFOAM
Fulltext is available at external website.
On Reynolds-averaged turbulence modeling with immersed boundary method
The immersed boundary (IB) method is an approach in the computational fluid dynamics in which complex geometry conforming meshes are replaced by simple ones and the true simulated geometry is ...
Finite element modal analysis of a silicone vocal fold filled with fluid
Hájek, P.; Radolf, Vojtěch; Horáček, Jaromír; Švec, J. G.
2023 - English
A three dimensional (3D) finite element (FE) model of a silicone vocal fold (VF) filled with fluid is presented here. The silicone part of the model is based on partial differential equations of the continuum mechanics and consider large deformations. The fluid domain encapsulated in the silicone VF is defined semianalytically as a lumped-element model describing the fluid in hydrostatic conditions. The elongated and pressurized silicone VF was subjected to perturbed modal analysis. Results showed that the choice of the fluid inside the VF substantially influences the natural frequencies. Namely, the water-filling lowers the natural frequencies approximately by half over the air-filling. Besides, the procedure of reverse engineering for obtaining the geometry of the VF from already 3D-printed mold is introduced.
Keywords:
perturbed modal analysis; finite element method; vocal folds; reverse engineering; biomechanics of voice
Fulltext is available at external website.
Finite element modal analysis of a silicone vocal fold filled with fluid
A three dimensional (3D) finite element (FE) model of a silicone vocal fold (VF) filled with fluid is presented here. The silicone part of the model is based on partial differential equations of the ...
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