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Počet nalezených dokumentů:
143
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Pilot scale production of a dietary supplement.
Prell, Aleš; Kujan, Petr; Sobotka, Miroslav; Šafář, Hynek; Vavruška, Tomáš
2016 - anglický
Pilot scale cultivations of biotransformation enzymes producer, the biotransformation of the dietary supplement and its DSP.
Klíčová slova:
dietary supplements; fungal fermentation
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Pilot scale production of a dietary supplement.
Pilot scale cultivations of biotransformation enzymes producer, the biotransformation of the dietary supplement and its DSP.
Development of the anaerobic submerged cultivation.
Prell, Aleš; Kujan, Petr; Sobotka, Miroslav; Šafář, Hynek; Vavruška, Tomáš
2016 - anglický
Development of the anaerobic cultivation of bacteria with a specific lipopolysaccharide content in the cell structures.
Klíčová slova:
anaerobic cultivation
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Development of the anaerobic submerged cultivation.
Development of the anaerobic cultivation of bacteria with a specific lipopolysaccharide content in the cell structures.
New inorganic matrices for pultrusion technology II
Černý, Zbyněk
2016 - anglický
Development of inorganic matrix enabling rapid continuous preparation of thermally and chemically stable and fire resistant materials with controlled properties for nuclear industry.
Klíčová slova:
inorganic matrices
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
New inorganic matrices for pultrusion technology II
Development of inorganic matrix enabling rapid continuous preparation of thermally and chemically stable and fire resistant materials with controlled properties for nuclear industry.
39M-IMMEDIATE Research Report: Remarks on Repeatability Experiments and Perspective Exploitation of MAE Pt/C\nElectrocatalysts.
Kaluža, Luděk; Gulková, Daniela; Soukup, Karel
2016 - anglický
The 36-39 months of the projekt solution were devoted to summarize aspects of the most perspective results on Pt/C electrocatalysts preparation to focus on industrial expoitation. Chellenges of Pt dispersion in the Pt/C were compared with preliminary outcomes from volumetric determination of hydrogen adsorption.
Klíčová slova:
Pt/c electrocatalysts; industrial exploitation; hydrogen absorption
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
39M-IMMEDIATE Research Report: Remarks on Repeatability Experiments and Perspective Exploitation of MAE Pt/C\nElectrocatalysts.
The 36-39 months of the projekt solution were devoted to summarize aspects of the most perspective results on Pt/C electrocatalysts preparation to focus on industrial expoitation. Chellenges of Pt ...
Evaluation of efficacy and bio-distribution of AAV5-miHTT in HD minipig brain
Bohuslavová, Božena; Juhás, Štefan; Juhásová, Jana; Ellederová, Zdeňka; Motlík, Jan
2016 - anglický
Healthy minipigs (n=29) were pre-screened for serum AAV5 neutralizing antibodies (NABs) in serum by uniQure. Conclusions: Intrastriatal/intrathalamic bilateral application of AAV5-CAG-miHtt(3e13/1e13gctotal) or PBS/Sucrose (54μl/216μl) similarly to AA5-CAG-GFP didn´t cause any neurological deficit in transgenic as well as wild type animals. The body weight increased in all animals 84 days after AAV5-CAG-miHtt/PBS-Sucroseintrastriatal/intrathalamic delivery with two exceptions TGanimal L616 (AAV5-CAG-miHtt1e 13g ctotal) and WTanimal L485 (AAV5-CAG-miHtt3e13gc total). The TG boar N176 from group VII (PBS/Sucrose) died during narcosis 56 days after IP/IT application), shortly after CSF and blood collection.The boar breathed heavily and intermittently, then the heart stopped beat and resuscitation failed. We immediately flushed them by 20 L of PBS with heparin and collect all tissues. All animals had normal food consumption. Inflammatory proces in AAV5-CAG-miHtt (1e13 gc total) seems to be similar to PBS/Sucrose injected animals accompanied with no detectable histological pathologies.
Klíčová slova:
minipig; Huntington´s disease
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Evaluation of efficacy and bio-distribution of AAV5-miHTT in HD minipig brain
Healthy minipigs (n=29) were pre-screened for serum AAV5 neutralizing antibodies (NABs) in serum by uniQure. Conclusions: Intrastriatal/intrathalamic bilateral application of ...
Development of pilot production technology of phosphorylases.
Prell, Aleš; Kujan, Petr; Sobotka, Miroslav; Šafář, Hynek; Vavruška, Tomáš
2016 - anglický
Development and optimization of the production of phosporylases for pharmaceutical industry. Cultivation technology and down-stream processing.
Klíčová slova:
enzyme production
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Development of pilot production technology of phosphorylases.
Development and optimization of the production of phosporylases for pharmaceutical industry. Cultivation technology and down-stream processing.
Cultivation and DSP of the Pseudomonas bacteria to produce low molecular natural compounds.
Prell, Aleš; Kujan, Petr; Sobotka, Miroslav; Šafář, Hynek; Vavruška, Tomáš
2016 - anglický
The set-up of the pilot cultivation of Pseudomonas spp. bacteria to produce specific low molecular natural compounds for pharmaceutical purposes.
Klíčová slova:
natural substances production
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Cultivation and DSP of the Pseudomonas bacteria to produce low molecular natural compounds.
The set-up of the pilot cultivation of Pseudomonas spp. bacteria to produce specific low molecular natural compounds for pharmaceutical purposes.
Optimization of media for cultivation of the bacterium E. coli with specific proteins in the cell wall.
Prell, Aleš; Kujan, Petr; Sobotka, Miroslav; Šafář, Hynek; Vavruška, Tomáš
2016 - anglický
Optimization of media for preparation of bacterial culture for isolation of specific proteins.
Klíčová slova:
microbial production
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Optimization of media for cultivation of the bacterium E. coli with specific proteins in the cell wall.
Optimization of media for preparation of bacterial culture for isolation of specific proteins.
Sharing of Czech Experience: Piloting SEEA-EEA in the Kyrgyz Republic
Vačkář, David; Harmáčková, Veronika Zuzana; Sylla, Marta; Grammatikopoulou, Ioanna; Whitham, Charlote; Emmer, Adam; Pártl, Adam
2016 - anglický
The report summarises the activities conducted within the project “Sharing of Czech Experience: Piloting SEEA-EEA in the Kyrgyz Republic”. The project was led by the Department of Human Dimensions of Global Change, Global Change Research Institute, Czech Academy of Sciences, with support from the Czech-UNDP Trust Fund (CTF). This 6-month project worked closely with several key stakeholders in the Kyrgyz Republic including primarily: The National Statistical Committee (NSC), The State Agency for Environment Protection and Forestry (SAEPF) and the United Nations Development Programme (UNDP). The aims of the project were to build capacity for experimental ecosystem accounting (SEEA EEA) in the form of three stakeholder consultation workshops and continuous project collaboration with Kyrgyz partners and experts, mapping and mobilizing available data sources for SEEA EEA, and compiling pilot experimental ecosystem accounts for the Kyzyl Unkur leshoz in collaboration with project partners in the Kyrgyz Republic.
Klíčová slova:
Ecosystem accounting; environmental statistics; ecosystem services; capacity building; stakeholder consultation
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Sharing of Czech Experience: Piloting SEEA-EEA in the Kyrgyz Republic
The report summarises the activities conducted within the project “Sharing of Czech Experience: Piloting SEEA-EEA in the Kyrgyz Republic”. The project was led by the Department of Human Dimensions of ...
Phenotypic Analyses of the HD transgenic Minipig Model
Motlík, Jan; Ellederová, Zdeňka
2016 - anglický
The transgenic model of Huntington’s disease in minipig (TgHD) was created in 2009 and information coding the sequence of N-terminal part of human mutated huntingtin was transferred to subsequent generations from both female and male sides. In each litter, transgenic (TgHD) and wild-type (WT) piglets were born in approximately equal ratio. At present, the Laboratory of Cell Regeneration and Plasticity keeps sets of animals in F2 and F3 generations with identical genetic background and bred in identical conditions of feeding and housing. The present research project was focused on a complex of non-invasive and invasive approaches to WT and TgHD minipigs to achieve the entire phenotypic analysis of HD progression in this large animal model.
Klíčová slova:
minipig
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Phenotypic Analyses of the HD transgenic Minipig Model
The transgenic model of Huntington’s disease in minipig (TgHD) was created in 2009 and information coding the sequence of N-terminal part of human mutated huntingtin was transferred to subsequent ...
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