Modeling of nucleolar self-assembly
Blažíková, Michaela; Heřman, P.; Malínský, Jan
2010 - anglický
Mammalian cell nucleoli disassemble at the beginning of mitosis and reassemble again during telophase and the early G1. Dynamics of this process was studied using a model based on entropy driven self-assembly of pre-ribosomal particles generated in a single biosynthetic source. Monte Carlo simulations revealed that such model can explain formation of a large aggregate, a nucleolus, in the vicinity of the source. We examined influence of nucleoplasm properties on dynamics of the aggregate formation.
Klíčová slova:
Monte Carlo simulations
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Modeling of nucleolar self-assembly
Mammalian cell nucleoli disassemble at the beginning of mitosis and reassemble again during telophase and the early G1. Dynamics of this process was studied using a model based on entropy driven ...
NANOTECHNOLOGY AND BIOMATERIALS IN MEDICINE
Kubinová, Šárka; Jendelová, Pavla; Lesný, Petr; Holáň, Vladimír; Syková, Eva
2009 - anglický
Our studies focus on the use of nanotechnology in cell therapy and tissue engineering for the treatment of brain and spinal cord injury, corneal defects and chronic wounds.
Klíčová slova:
superparamagnetic iron oxide; mesenchymal stem cells; embryonic stem cells
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
NANOTECHNOLOGY AND BIOMATERIALS IN MEDICINE
Our studies focus on the use of nanotechnology in cell therapy and tissue engineering for the treatment of brain and spinal cord injury, corneal defects and chronic wounds.
Role of glial cells in extrasynaptic communication
Syková, Eva
2003 - anglický
It is evident that during neuronal activity and pathological states, the movement of substances in the brain is not only hindered by the size of the pores between the cells, but also by the structure of the glial cells. These changes, together with K+ and pH changes in the ECS, affect the efficacy of interneuronal and neurone-glia communication.
Klíčová slova:
Glial cells; extrasynaptic communication
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Role of glial cells in extrasynaptic communication
It is evident that during neuronal activity and pathological states, the movement of substances in the brain is not only hindered by the size of the pores between the cells, but also by the structure ...
Human embryonic stem cell line originating from blastocyst produced by intracytoplasmic sperm injection
Hampl, Aleš; Jendelová, Pavla; Syková, Eva; Dvořák, Petr
2003 - anglický
The biological properties of the AL1 ES cell line will be assessed by introducing the cells into the brains of adult Wistar rats following a unilateral cortical photochemical lesion.
Klíčová slova:
Human embryonic stem cell
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Human embryonic stem cell line originating from blastocyst produced by intracytoplasmic sperm injection
The biological properties of the AL1 ES cell line will be assessed by introducing the cells into the brains of adult Wistar rats following a unilateral cortical photochemical lesion.
Detekce molekulárních znaků embryonálních kmenových buněk
Dvořák, Petr; Bryja, Vítězslav; Pacherník, Jiří; Hampl, Aleš
2003 - český
Klíčová slova:
stem cell
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Detekce molekulárních znaků embryonálních kmenových buněk
Lewis X, developmentally regulated carbohydrate is abundantly expressed in embryonic and adult neural stem cells and regulates their self-renewal and/or differentiation
Dvořák, Petr; Hampl, Aleš
2003 - anglický
Klíčová slova:
neural stem cell
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Lewis X, developmentally regulated carbohydrate is abundantly expressed in embryonic and adult neural stem cells and regulates their self-renewal and/or differentiation
Stem cells and therapy of brain and spinal cord injury
Syková, Eva; Jendelová, Pavla; Růžičková, Kateřina; Machová-Urdzíková, Lucia; Lesný, Petr; Hampl, Aleš; Dvořák, Petr
2003 - anglický
Our studies demonstrate the potential of SC as a therapeutic tool in the treatment of injury and degenerative diseases, explain the effects of certain drugs on neurogenesis and regeneration and show that there may be various ways in which SC may interact with the host CNS tissue.
Klíčová slova:
stem cells
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Stem cells and therapy of brain and spinal cord injury
Our studies demonstrate the potential of SC as a therapeutic tool in the treatment of injury and degenerative diseases, explain the effects of certain drugs on neurogenesis and regeneration and show ...
Diffusion properties of the brain in health and disease
Syková, Eva
2003 - anglický
Diffusion parameters affect neurone-glia communication, ionic homeostasis, the movement and accumulation of neuroactive substances and, therefore, play an important role in synaptic as well as volume transmission.
Klíčová slova:
Diffusion properties; brain
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Diffusion properties of the brain in health and disease
Diffusion parameters affect neurone-glia communication, ionic homeostasis, the movement and accumulation of neuroactive substances and, therefore, play an important role in synaptic as well as volume ...
Implantation of bone marrow stromal cells labeled with superparamagnetic nanoparticles into injured brain and imaging their fate by magnetic resonance
Jendelová, Pavla; Herynek, V.; Růžičková, Kateřina; Hájek, M.; Syková, Eva
2003 - anglický
Our study demonstrates that MSCs only migrate into an injured brain region. The commercially available contrast agent Endorem can be used as a cell marker for noninvasive MR tracking of implanted stem cells.
Klíčová slova:
bone marrow stromal cells; nanoparticles
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Implantation of bone marrow stromal cells labeled with superparamagnetic nanoparticles into injured brain and imaging their fate by magnetic resonance
Our study demonstrates that MSCs only migrate into an injured brain region. The commercially available contrast agent Endorem can be used as a cell marker for noninvasive MR tracking of implanted stem ...
Changes in intrinsic optical signals and extracellular space diffusion parameters. Do they have a common mechanism?
Chvátal, Alexandr; Vargová, Lýdia; Kubinová, Šárka; Syková, Eva
2003 - anglický
We can therefore conclude that light transmittance changes do not simply correlate with changes in ECS volume, but they are clearly associated with neuronal activity accompanied by various biochemical, biophysical and morphological changes.
Klíčová slova:
Intrinsic optical signals; extracellular space; common mechanism
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Changes in intrinsic optical signals and extracellular space diffusion parameters. Do they have a common mechanism?
We can therefore conclude that light transmittance changes do not simply correlate with changes in ECS volume, but they are clearly associated with neuronal activity accompanied by various ...
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