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4th CCP Phenogenomics Conference abstract book
Sedláček, Radislav
2022 - anglický
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic focus of the 2022 Conference. The Conference provided again an excellent opportunity to support networking and interactions among the researchers, CCP staff, users and experts from the commercial sector.
Klíčová slova:
phenogenomics; rare diseases; gene therapy; experimental models; delivery of therapies
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
4th CCP Phenogenomics Conference abstract book
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic ...
4th CCP Phenogenomics Conference abstract book
Sedláček, Radislav
2022 - anglický
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic focus of the 2022 Conference. The Conference provided again an excellent opportunity to support networking and interactions among the researchers, CCP staff, users and experts from the commercial sector.
Klíčová slova:
phenogenomics; rare diseases; gene therapy; experimental models; delivery of therapies
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
4th CCP Phenogenomics Conference abstract book
The fourth CCP Phenogenomics Conference was held as a hybrid meeting. The scientific committee selected the topic of rare diseases: experimental models & delivery of therapies as the main thematic ...
3rd CCP Phenogenomics Conference 2021: Abstract Book
Sedláček, Radislav
2021 - anglický
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including covid-19, which focused on translation of the basic research into the application. The Conference provided an excellent opportunity to support networking and interactions among the CCP users and experts.
Klíčová slova:
phenogenomics; human diseases; mouse models; preclinical development; covid-19
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
3rd CCP Phenogenomics Conference 2021: Abstract Book
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including ...
2nd CCP Phenogenomics Conference 2020: Abstract Book
Sedláček, Radislav
2020 - anglický
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including covid-19, which focused on translation of the basic research into the application. The Conference provided an excellent opportunity to support networking and interactions among the CCP users and experts.
Klíčová slova:
phenogenomics,; human diseases; mouse models; preclinical development
Plné texty jsou dostupné v digitálním repozitáři NUŠL
2nd CCP Phenogenomics Conference 2020: Abstract Book
The Conference was divided into two blocks. The first day was devoted to the theme “Human diseases and models“. The second day was specifically dedicated to preclinical development, including ...
2nd CCP Phenogenomics Conference 2020
Sedláček, Radislav
2020 - anglický
The conference was divided into two blocks. The block focused on the theme “From chemistry via preclinical pipeline to therapeutics“, which emphasized the translation of the basic research into the application. The second block was specifically devoted to presentation of CCP users and cooperation partners projects working in the field of immunology, hematology, genetic base of diseases, and neurobiology.
Klíčová slova:
Phenogenomics; therapeutics; immunity; genetic base of diseases
Plné texty jsou dostupné v digitálním repozitáři Akademie Věd.
2nd CCP Phenogenomics Conference 2020
The conference was divided into two blocks. The block focused on the theme “From chemistry via preclinical pipeline to therapeutics“, which emphasized the translation of the basic research into the ...
Mikroskopie 2008
Hozák, Pavel
2008 - český
Dvoudenní konference reagující na nejnovější trendy v světelné a elektronové mikroskopii a jejich dopad na mikroskopické badatele v českých zemích a na slovensku. Prezentovány jsou příspěvky jak z oblasti biomedicínské, tak z oblasti fyziky a materiálových věd. Konference se koná v lyžařském sportovním areálu v srdci českomoravské vysočiny a je zakončena opulentním rautem s ochutnávkou vín. Two-day conference responding to novel trends in light and electron microscopy and their impact on researchers in the Czech Republic and Slovakia. Contributions were presented in biomedical as well as physics and material science fields. The Conference was held in a sports area in the heart of the Czech-Moravian Heights and was closed by an opulent rout with wine degustation.
Klíčová slova:
light microscopy; electron microscopy
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Mikroskopie 2008
Dvoudenní konference reagující na nejnovější trendy v světelné a elektronové mikroskopii a jejich dopad na mikroskopické badatele v českých zemích a na slovensku. Prezentovány jsou příspěvky jak z ...
Binding properties of boar seminal plasma proteins in the reproduction process
Jonáková, Věra; Maňásková, Pavla; Liberda, J.; Tichá, M.
2005 - anglický
Boar seminal plasma proteins (spermadhesins and DQH protein)bind the sperm surface at ejaculation. binding of sperm to oviductal epithelial cells and to the glycoproteins of zona pellucida are mediated by the protein-saccharide (lectin-like)interactions.These intractions play role in the formation of sperm oviductal reservoir, in the release of capacitated sperm from the surface of oviduct and in sperm-zona pellucida interaction. Proteiny kančí semenné plasmy (spermadhesiny a DQH protein) se váží na povrch spermie při ejakulaci. Vazba spermie k epiteliálním buňkám oviduktu a ke glykoproteinům zony pellucidy je zprostředkována protein-sacharidovými interakcemi (lektin-like).Tyto interakce hrají roli v tvorbě oviduktálního rezervoáru spermií, v uvolnění kapacitovaných spermií z povrchu oviduktu a ve vazbě spermie na zonu pellucidu vajíčka.
Klíčová slova:
seminal plasma proteins; reproduction; binding properties
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Binding properties of boar seminal plasma proteins in the reproduction process
Boar seminal plasma proteins (spermadhesins and DQH protein)bind the sperm surface at ejaculation. binding of sperm to oviductal epithelial cells and to the glycoproteins of zona pellucida are ...
The origin of boar seminal plasma proteins
Maňásková, Pavla; Kyselová, Vendula; Tichá, M.; Jonáková, Věra
2005 - anglický
Spermadhesins were detected with their antibodies in boar epididymal fluid, but DQH and beta-microseminoprotein were not. Indirect immunofluorescence technique was employed to determine the distribution of seminal plasma proteins on tissue sections of the reproductive organs. The mRNA of the DQH was found only in seminal vesicles, not in the epididymis, and the mRNA of beta-MSP in testis, seminal vesiclas and prostate. Spermadhesiny byly nalezeny pomocí svých protilátek v kančí epididymální tekutině, ale DQH a beta microseminoprotein nikoli. Nepřímá imunofluorescenční technika byla použita pro odhalení distribuce proteinů semenné plasmy na řezech tkání kančích reprodukčních orgánů. mRNA beta-MSP v testes, semenných vacích a prostatě.
Klíčová slova:
seminal plasma proteins; boar reproductive organs
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
The origin of boar seminal plasma proteins
Spermadhesins were detected with their antibodies in boar epididymal fluid, but DQH and beta-microseminoprotein were not. Indirect immunofluorescence technique was employed to determine the ...
Regulation of ribosome synthesis in bacteria
Krásný, Libor
2005 - anglický
Rapidly growing bacteria need a high number of ribosomes to satisly the cells need for increased translation. Starving bacteria need a low number of ribosomes to limit energy expenditure.The number of ribosomes is regulated at the level of ribosomal RNA (rRNA) transcription. Rychle rostoucí bakterie potřebují velké množství ribozomů pro pokrytí potřeby zvýšené buněčné translace. Bakterie v podmínkách omezené výživy mají potřebu ribozomů nízkou kvůli šetření energií. Počet ribozomů je regulován na úrovni transkripce ribozomální RNA (rRNA).
Klíčová slova:
ribosome synthesis; bacteria
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Regulation of ribosome synthesis in bacteria
Rapidly growing bacteria need a high number of ribosomes to satisly the cells need for increased translation. Starving bacteria need a low number of ribosomes to limit energy expenditure.The number of ...
Carbonic anhydrase IX (CA IX) mediates tumor cell interactions with microenvironment
Závada, Jan; Závadová, Zuzana
2004 - anglický
CA IX zprostředkuje vzájemné reakce nádorových buněk s mikroprostředím několika způsoby: je enzymaticky aktivní, reguluje pH a řídí přenos iontů z/do buňky; CA IX je také adhezivní molekulou zprostředkující mezibuněčný kontakt; slouží jako senzor pH a účastní se invaze a metastáze nádorů CA IX mediates interaction between tumor cells and microenvironment in several ways: it is enzymatically active, it regulates pH and drives ion transport from/to the cell; CA IX is also an adhesion molecule, mediating cell-cell contact; it serves as a pH sensor and it participates in tumor invasion and metastasis
Klíčová slova:
cancer biology; microenvironmnet; carbonic anhydrase IX; nádorové buňky; buňky
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Carbonic anhydrase IX (CA IX) mediates tumor cell interactions with microenvironment
CA IX zprostředkuje vzájemné reakce nádorových buněk s mikroprostředím několika způsoby: je enzymaticky aktivní, reguluje pH a řídí přenos iontů z/do buňky; CA IX je také adhezivní molekulou ...
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