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MR tracking of transplanted stem cells labeled by iron-oxide nanoparticles
Syková, Eva; Jendelová, Pavla
2003 - anglický
Our study demonstrates that grafted MSC and ESC migrate into an injured brain region. The commercially available contrast agent Endorem, based on iron-oxide nanoparticles, can be used a marker for long-term noninvasive MR tracking of implanted stem cells.
Klíčová slova:
Stem cells; nanoparticles
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
MR tracking of transplanted stem cells labeled by iron-oxide nanoparticles
Our study demonstrates that grafted MSC and ESC migrate into an injured brain region. The commercially available contrast agent Endorem, based on iron-oxide nanoparticles, can be used a marker for ...
Diffusion and MRS in a rat cortex after traumatic injury
Voříšek, Ivan; Herynek, V.; Burian, M.; Hájek, M.; Niclay, K.; Syková, Eva
2001 - anglický
An increase in diffusion barriers, manifestes by a decrease of both ADCTMA and ADCW, occurs throughout the entire cortex of the wounded hemisphere. These changes are related to astrogliosis and to an accumulation of extracellular matrix molecules without significant changes in ECS volume.
Klíčová slova:
astrogliosis
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Diffusion and MRS in a rat cortex after traumatic injury
An increase in diffusion barriers, manifestes by a decrease of both ADCTMA and ADCW, occurs throughout the entire cortex of the wounded hemisphere. These changes are related to astrogliosis and to an ...
Learning, MRI and structural changes of the rat hippocampus 1 ro 12 months after irradiation with the leksell gamma knife
Náměstková, Kateřina; Liščák, R.; Herynek, V.; Burian, M.; Jirák, D.; Hájek, M.; Brožek, G.; Mareš, V.; Syková, Eva
2001 - anglický
The lower the dose of irradiation with the LKG, the more delayed are the structural and functional changes in hippocampus.
Klíčová slova:
leksell gamma knife
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Learning, MRI and structural changes of the rat hippocampus 1 ro 12 months after irradiation with the leksell gamma knife
The lower the dose of irradiation with the LKG, the more delayed are the structural and functional changes in hippocampus.
Alterated diffusion parameters in the brain with kaolin-induced hydrocephalus
Fiala, Jindřich; Antonova, Tatiana; Voříšek, Ivan; Syková, Eva
2001 - anglický
Compression of the ECS in the cerebral cortex following induction of hydrocephalus, slows down the diffusion of neuroactive substances in hydrocephalic tissue.
Klíčová slova:
hydrocephalus
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Alterated diffusion parameters in the brain with kaolin-induced hydrocephalus
Compression of the ECS in the cerebral cortex following induction of hydrocephalus, slows down the diffusion of neuroactive substances in hydrocephalic tissue.
Extracellular space size and geometry in the brain of APP23 mice representing a model of Alzheimer´s disease
Mazel, Tomáš; Antonova, Tatiana; Meyer-Luhmann, M.; Staufenbiel, M.; Jucker, M.; Syková, Eva
2001 - anglický
The decrease in ECS size observed during aging might contribute to increased extracellular amyloid concentration and deposition in APP23 mice.
Klíčová slova:
Alzheimer´s
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Extracellular space size and geometry in the brain of APP23 mice representing a model of Alzheimer´s disease
The decrease in ECS size observed during aging might contribute to increased extracellular amyloid concentration and deposition in APP23 mice.
Nucleoli of naked megakaryocytic nuclei
Janoutová, J.; Likovský, Zbyněk
2001 - anglický
The differentiation and maturation of megakaryocytes is characterized by endomitotic divisions which result in the formation of large polyploid cells the cytoplasm of which is segregated as thrombocytes. The present study was undertaken to provide more information on the incidence of nucleoli in naked magakaryocytic nuclei representing terminal stages of the megakaryocytic development after the loss of the cytoplasm transformed to thrombocytes.
Klíčová slova:
nucleoli; megakaryocytes
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Nucleoli of naked megakaryocytic nuclei
The differentiation and maturation of megakaryocytes is characterized by endomitotic divisions which result in the formation of large polyploid cells the cytoplasm of which is segregated as ...
Morphology and distribution of nadph-diaphorase-positive neurons in the auditory cortex of the rat
Nwabueze-Ogbo, Fidel Chijoke; Druga, R.; Syka, Josef
2001 - anglický
Our results indicate the preferred localization of the NADPH-d/NOS positive neurons in the infragranular layers, which are sources of the majority of corticofugal neurons projecting to the subcortical structures.
Klíčová slova:
nadph-diaphorase-positive
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Morphology and distribution of nadph-diaphorase-positive neurons in the auditory cortex of the rat
Our results indicate the preferred localization of the NADPH-d/NOS positive neurons in the infragranular layers, which are sources of the majority of corticofugal neurons projecting to the subcortical ...
Functional characteristics of neurons in the auditory thalamus
Kvašňák, Eugen; Šuta, Daniel; Popelář, Jiří; Syka, Josef
2001 - anglický
The MGB, is similarly as the inferior colliculus (IC) is organized into three subdivisions, with the ventral MGB characterized by the quickest onset reaction with the lowest thresholds to auditory stimulation and with the same ratio of monotonic and non-monotonic RLFs.
Klíčová slova:
auditory thalamus
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Functional characteristics of neurons in the auditory thalamus
The MGB, is similarly as the inferior colliculus (IC) is organized into three subdivisions, with the ventral MGB characterized by the quickest onset reaction with the lowest thresholds to auditory ...
A behavioral and electrophysiological study of the effects of noise exposure on auditory function in rat
Rybalko, Natalia; Mazelová, Jana; Syka, Josef
2001 - anglický
The values of the gap detection threshold doubled after exposure to 110 dB SPL and quadrupled after exposure to 115-120 dB SPL. GDT recovered to the original values during 1-2 weeks. Increased gap detection thresholds after noise exposure appear connected with elevated hearing thresholds, the deterioration in the performance of some animals in behavioral rasts after strong intensity noise (120 dB SPL) may signal the occurrence of tinnitus in these animals.
Klíčová slova:
auditory system
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
A behavioral and electrophysiological study of the effects of noise exposure on auditory function in rat
The values of the gap detection threshold doubled after exposure to 110 dB SPL and quadrupled after exposure to 115-120 dB SPL. GDT recovered to the original values during 1-2 weeks. Increased gap ...
Neuron-glia communication by extrasynaptic transmission
Syková, Eva
2001 - anglický
Dynamic changes in ECS ionic composition, volume and geometry accompany neuronal activity, neuronal loss, glial development and proliferation, aging, CNS injury, anoxia/ischemia, spreading depression, tumors, inflammation dyemyelination and many other brain pathological states.
Klíčová slova:
neuronal activity
Plné texty jsou dostupné na jednotlivých ústavech Akademie věd ČR.
Neuron-glia communication by extrasynaptic transmission
Dynamic changes in ECS ionic composition, volume and geometry accompany neuronal activity, neuronal loss, glial development and proliferation, aging, CNS injury, anoxia/ischemia, spreading depression, ...
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